Sunglasses from Goodrich Optical are a popular accessory many people wear to protect their eyes from the sun's harmful rays. However, you may not be aware of the actual science behind sunglasses and how they protect our eyes. Lets explore the science behind sunglasses and how they protect our eyes from the sun.
With age, you might have difficulty focusing on objects up close. You may become more sensitive to glare and have trouble adapting to different levels of light. Let’s look at some of the more common eye problems related to aging:
Menopause is the cessation of the menstrual cycle in a woman. Women experience symptoms such as hot flashes, mood swings, etc as their bodies adjust to lower levels of estrogen and progesterone. All women experience menopause differently. Some experience metabolic changes, weight loss or weight gain, and urinary tract infections among other changes. Others may not experience any changes at all.
October is observed every year as Blindness Awareness Month, which focuses on understanding and supporting the problems faced by blind people. According to the World Health Organization, about 2.2 billion people worldwide suffer from visual impairment or blindness.
Posterior uveitis is a rare eye disease that can damage the retina and the optic nerve, which may result in permanent blindness. It can affect a person of any age, even children, and may lead to the loss of vision in one or both eyes.
Your eyes do not deceive you: Many women discover that they have blurry vision during pregnancy. No need to panic, though. Your vision will likely return to normal in the blink of an eye. Blurry vision during pregnancy is more common than you think, and sometimes sticks around until after you deliver.
Experts from buck institute reveal a connection between diet, eye health and life expectancy in Drosophila. They find that the processes in the fly’s eye drive the ageing process. Previous studies have shown an association between eye disorders and poor health in humans.
Researchers from the National Eye Institute (NEI) have identified a new disease that affects the macula, a small part of the light-sensing retina needed for sharp, central vision. Scientists report their findings on the novel macular dystrophy, which is yet to be named, in JAMA Ophthalmology. NEI is part of the National Institutes of Health.
Macular dystrophies are disorders that usually cause central visual loss because of mutations in several genes, including ABCA4, BEST1, PRPH2, and TIMP3.
For example, patients with Sorsby Fundus Dystrophy, a genetic eye disease specifically linked to TIMP3 variants, usually develop symptoms in adulthood. They often have sudden changes in visual acuity due to choroidal neovascularization- new, abnormal blood vessels that grow under the retina, leaking fluid and affecting vision.
TIMP3 is a protein that helps regulate retinal blood flow and is secreted from the retinal pigment epithelium (RPE), a layer of tissue that nourishes and supports the retina’s light-sensing photoreceptors. All TIMP3 gene mutations reported are in the mature protein after it has been “cut” from RPE cells in a process called cleavage.
“We found it surprising that two patients had TIMP3 variants not in the mature protein, but in the short signal sequence the gene uses to ‘cut’ the protein from the cells. We showed these variants prevent cleavage, causing the protein to be stuck in the cell, likely leading to retinal pigment epithelium toxicity,” said Bin Guan, Ph.D., lead author.
The research team followed these findings with clinical evaluations and genetic testing of family members to verify that the two new TIMP3 variants are connected to this atypical maculopathy.
“Affected individuals had scotomas, or blind spots, and changes in their maculas indicative of disease, but, for now, they have preserved central vision and no choroidal neovascularization, unlike typical Sorsby Fundus Dystrophy,” said Cathy Cukras, M.D., Ph.D., a Lasker tenure-track investigator and medical retina specialist who clinically evaluated the patients.
NEI’s Ophthalmic Genomics Laboratory gathers and manages specimens and diagnostic data from patients who have been recruited into multiple studies within the NEI clinical program to facilitate research of rare eye diseases, including Sorsby Fundus Dystrophy.
“Discovering novel disease mechanisms, even in known genes like TIMP3, may help patients that have been looking for the correct diagnosis, and will hopefully lead to new therapies for them,” said Rob Hufnagel, M.D., Ph.D., senior author and director of the Ophthalmic Genomics Laboratory at NEI.
The study was funded by the NEI Intramural Research Program.
We have all experienced headaches. Most adults get a headache every now and then, but how do you know if your headache is serious? The term "ocular migraine" can be confusing. It generally means a headache that's accompanied by changes in vision. The term is often used interchangeably to refer to two different conditions: migraine with aura.
Reduced blood flow and impaired neurovascular coupling are well-known features of glaucoma, the main cause of non-curable blindness, affecting 80 million people worldwide in 2020. The mechanisms behind these abnormalities are now known, thanks to new research by a team led by Adriana Di Polo, professor of neuroscience and ophthalmology at Université de Montréal. The findings by Luis Alarcon-Martinez and Yukihiro Shiga, both post-doctoral fellows in Di Polo’s laboratory and co-authors of the study, reveal that nanotubes connecting pericytes are damaged in glaucoma leading to neurovascular failures.
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